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Thanks for sharing all this information! Really enjoy the webinars, hope this becomes the norm.
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That’s the plan! I’ll probably do one a month if there’s a good response. In the meantime, you can browse “Thib talks training” where I’ve posted over 20 videos on various training topics.
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Hi CT, I’m the one asking the question about the combination of beta blockers, clen and T3 for weight loss. I ask because Lyle McDonald writes in one of his books that beta blockers combined with stimulants increase fat loss, on the other hand the older beta blockers alone cause weight gain. (This does not happen with third generation beta blockers)
– A peptide called atrial natriuretic peptide (ANP) is released by the heart.
-Beta-blockers stimulate the release of ANP, which contributes to fat mobilization.
“(…) Oral β-adrenoceptor blockers enhance cardiac exercise-induced ANP release and may contribute to lipid mobilization in SCAT (…).”
Moro C, Crampes F, Sengenes C, De Glisezinski I, Galitzky J, Thalamas C, Lafontan M, Berlan M. Atrial natriuretic peptide contributes to physiological control of lipid mobilization in humans. FASEB J. 2004 May; 18
So, in theory you can accelerate fat loss because more fat is mobilized, the thing is, not everything that makes sense in theory translates to real world results, I find it weird, I’ve never heard to others who have talked about this.
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When I’m walking on the treadmill at 3mph, I usually do 115 steps, from 60 to 80. Seems like you might be walking at 2mph? Another 10 minutes usually gets me about 1150 steps.
@Christian_Thibaudeau
What do you think of the flood of diet pills flooding the market?
Looks like there are some new brands of Biotest supplements. (click the 30% discount link)
That’s interesting. Haven’t heard of it either, and I don’t think many people in the training world have either. Thanks Lyle for always being impressive in research despite our personal differences.
Yes, that’s even better.I admit I’m a very slow walker (so I use what feels like my normal walking speed on the treadmill)…when I go for a walk with my wife I always tell her to stop sprinting lol
But that only makes the concept better
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I’m assuming you’re talking about semaglutide and other similar products.
Personally, I don’t like its hard-working mechanics. By killing your appetite, you eat a lot less. This is fine for obese people who overeat chronically and overeat more often.
But as someone who trains, I’m not sure if I want to use something that will suppress my appetite, which might make it harder for me to get the protein I need and possibly lead to insufficient food intake to support growth.
The one time I think it helps is at the tail end of background/photo prep, when the calories are already low and you start to have huge cravings. But other than that, I don’t like it.
Also, I recall reading something about less fat mobilization when you stop means greater rebound. Don’t quote me because I don’t remember where it came from.
But in general, I don’t like using drugs for things that just require discipline, motivation, and resilience.
I understand the need for meds to address specific physical issues (e.g. hypothyroidism, diabetes, high blood pressure, etc.), but I don’t like using meds for things you can achieve just by getting better.
I also find it ironic that drugs that allow you to build more muscle (steroids) are demonized, while semaglutide, which does the same thing as steroids but for weight loss, is all the rage and widely accepted by the general population.
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No, opposite. β2 agonistNot a beta blocker.
ancient history. Dan Duchaine proposed this method in Bodyopus in 1996. Lyle expands on this. The key word above is training, as anyone who pays attention to the pharmaceutical side knows this all too well.
EDIT: Misunderstood and misread the original post above. My fault.
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good idea. My prediction would be a huge mistake.Semaglutide is not free lunch. You can say that.
Sorry if I wasn’t clear, I didn’t say clen is a beta blocker, I said:
As a supplement, beta blockers, clen and T3, three different things put together.
I think you’re wrong, if you read what I’ve written, you’ll see that I’m not talking about the direct effect of Alpha and Beta receptors on fat loss (that’s what Dan Duchaine wrote about in “Bodyopus”). What I’m saying is that on beta blockers, the heart secretes a peptide called ANP that has been shown to affect fat mobilization and possibly improve fat loss.
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knew. Thanks for the clarification. My fault.
Reddit – dig deep into anythingyou need to be Dedicated go that way. I’ve learned the hard way to minimize heart risk as part of a fat loss regimen.
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No problem, thanks for the link, too bad that guy started a new thread with actual results, but it’s only been two weeks, too short a time to draw conclusions.
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Hi trainer, how does metformin generally affect insulin sensitivity, fat loss or weight lifting. I am 46 years old and only started lifting weights regularly 2 years ago. My doctor suggested metformin last year for borderline diabetes. 2 years ago I had a successful fat loss phase at the beginning of my training. Then I’ve done two fat loss and muscle gain sessions, and I’m starting to see my body getting back into shape. I train regularly and watch my diet.
Okay, let me start by saying that Metformin is one of the safest medications prescribed. It is also very effective and has been used for a long time. However, its exact mechanism of action is unknown to the best of my knowledge.
However, it is effective against pre-diabetic and even diabetic states. It does increase insulin sensitivity and improves the body’s storage of glucose, thereby reducing the need for large amounts of insulin production.
It appears to favor the storage of glucose within the muscles, but more importantly, it reduces the storage of glucose as fat.
And since it reduces insulin production, it may speed up your metabolic rate (high insulin slows your metabolic rate). Elevated insulin also reduces fat mobilization, so keeping it low will help too.
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Thanks Coach for the reply…it was very helpful in understanding how this drug is affecting my body.
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